Description

Glycine, n-[2-Amino-4-(Trifluoromethyl)Phenyl]-, Ethyl Ester is a specialized trifluoromethylated aromatic glycine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethyl substituent on the phenyl ring, makes it a valuable precursor for creating novel compounds with enhanced properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting receptor modulation.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioactivity.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for constructing complex heterocycles and functionalized aromatic systems.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	Glycine, n-[2-Amino-4-(Trifluoromethyl)Phenyl]-, Ethyl Ester
CAS No.	1178799-62-6
Molecular Formula	C11H11F3N2O2
Molecular Weight	260.21 g/mol
Synonyms	Ethyl 2-((2-Amino-4-(trifluoromethyl)phenyl)amino)acetate; 2-[(2-Amino-4-(trifluoromethyl)phenyl)amino]acetic Acid Ethyl Ester; N-(2-Amino-4-trifluoromethylphenyl)glycine Ethyl Ester; Glycine, N-[2-amino-4-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl N-(2-amino-α,α,α-trifluoro-p-tolyl)glycinate
EINECS	Contact for details

Quality Control

Every batch of Glycine, n-[2-Amino-4-(Trifluoromethyl)Phenyl]-, Ethyl Ester is produced and tested under a strict quality management system to ensure consistency and reliability for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.