Description

Boc-L-2,4-Dinitrophe is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex peptides and other bioactive molecules. It is particularly valuable in pharmaceutical R&D and fine chemical production, where precise molecular architecture is paramount.

Application

• Peptide Synthesis: Serves as a key intermediate in solid-phase and solution-phase peptide synthesis (SPPS), where the Boc (tert-butoxycarbonyl) group provides orthogonal protection for the amino functionality.
• Pharmaceutical Research: Used in the research and development of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those with complex peptide backbones.
• Bioconjugation: Acts as a reagent for the site-specific modification of peptides and proteins, leveraging the reactivity of the dinitrophenyl (Dnp) protecting group.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides and molecular probes for studying biological mechanisms and interactions.
• Fine Chemical Intermediate: Functions as a high-value precursor in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Item	Detail
Product Name	Boc-L-2,4-Dinitrophe
CAS No.	1176509-56-0
Molecular Formula	C15H19N3O8
Molecular Weight	369.33 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-ω-(2,4-dinitrophenyl)-L-homoarginine; Boc-HomoArg(Dnp)-OH; Boc-L-Homoarginine(Dnp)-OH; tert-Butyl N-[(2S)-5-[(2,4-dinitrophenyl)amino]-1-(hydroxyamino)-1-oxopentan-2-yl]carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-5-((2,4-dinitrophenyl)amino)pentanoic acid
EINECS	Contact for details

Quality Control

Every batch of Boc-L-2,4-Dinitrophe is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.