Description

(S)-2-n-Cbz-Aminomethylmorpholine CAS NO 1174913-73-5 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its protected amine and morpholine functionalities, which are crucial for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Peptidomimetic Chemistry: Used to introduce constrained morpholine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in transition metal catalysis.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	(S)-2-n-Cbz-Aminomethylmorpholine
CAS No.	1174913-73-5
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	(S)-4-((((Benzyloxy)carbonyl)amino)methyl)morpholine-2-carboxylic acid; (S)-2-Carboxy-4-(Cbz-aminomethyl)morpholine; (2S)-4-({[(Benzyloxy)carbonyl]amino}methyl)morpholine-2-carboxylic acid; (S)-N-Cbz-Aminomethylmorpholine-2-carboxylic Acid; (S)-2-Carboxy-N-Cbz-aminomethylmorpholine; Benzyl ((S)-2-carboxymorpholin-4-yl)methylcarbamate; Cbz-AMM (S-isomer)
EINECS	Contact for details

Quality Control

Our (S)-2-n-Cbz-Aminomethylmorpholine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.