Description

1,2-Difluoro-3-isopropoxybenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine substituents and an isopropoxy group, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the difluorophenoxy moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, contributing to improved charge transport, thermal stability, and optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, functionalized biaryl and heteroaryl systems.
• Polymer Chemistry: Can be incorporated as a monomer or modifier to develop specialty polymers with enhanced chemical resistance, lower dielectric constants, or specific surface properties.

Basic Information

Product Name	1,2-Difluoro-3-isopropoxybenzene
CAS No.	1174005-86-7
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	3-Isopropoxy-1,2-difluorobenzene; 1,2-Difluoro-3-(1-methylethoxy)benzene; Benzene, 1,2-difluoro-3-(1-methylethoxy)-; 2,3-Difluorophenyl isopropyl ether; Isopropyl 2,3-difluorophenyl ether
EINECS	Contact for details

Quality Control

Our 1,2-Difluoro-3-isopropoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.