Description

(R)-(+)-4-[2-(Diphenylphosphino)-1-Naphthalenyl]-n-[(S)-1-Phenylethyl]-1-Phthalazinamine is a sophisticated, chiral phosphine-phthalazine hybrid ligand designed for asymmetric catalysis. This compound matters because it provides exceptional stereocontrol in transition metal-catalyzed reactions, enabling the synthesis of high-value, enantiomerically pure intermediates. It is critically needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C and C-X bond-forming cross-coupling reactions.
• Key reagent in the development of novel organometallic catalysts for academic and industrial research.
• Use in the synthesis of enantiomerically pure agrochemicals and flavors & fragrances.
• Precursor for immobilized catalysts used in continuous flow chemistry applications.
• Critical material for process chemistry optimization in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	(R)-(+)-4-[2-(Diphenylphosphino)-1-Naphthalenyl]-n-[(S)-1-Phenylethyl]-1-Phthalazinamine
CAS No.	1173836-08-2
Molecular Formula	C₃₈H₃₀N₃P
Molecular Weight	559.64 g/mol
Synonyms	(R)-(+)-4-[2-(Diphenylphosphino)-1-naphthyl]-N-[(S)-1-phenylethyl]phthalazin-1-amine; (R)-(+)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(S)-1-phenylethyl]-1-phthalazinamine; (R)-(+)-4-[2-(Diphenylphosphino)-1-naphthyl]-N-[(S)-1-phenylethyl]phthalazin-1-amine; (R)-(+)-4-[2-(Diphenylphosphino)-1-naphthyl]-N-[(S)-1-phenylethyl]-1-phthalazinamine; Chiral Phthalazine-Phosphine Ligand; Asymmetric Phosphine Ligand; (R,S)-PPAP Ligand
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-[2-(Diphenylphosphino)-1-Naphthalenyl]-n-[(S)-1-Phenylethyl]-1-Phthalazinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and elemental analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and chiral purity to ensure consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.