Description

2-Amino-5-Bromo-4-Methoxybenzonitrile is a versatile brominated aniline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups, makes it a valuable intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where its bromine atom allows for further functionalization.
• Dye and Pigment Manufacturing: Serves as a starting material for producing high-performance, light-fast organic dyes and pigments.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and other functional materials due to its electron-donating and accepting properties.
• Cross-Coupling Reactions: Acts as a substrate in Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Amino-5-Bromo-4-Methoxybenzonitrile
CAS No.	1173713-05-7
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	5-Bromo-2-amino-4-methoxybenzonitrile; 4-Methoxy-5-bromo-2-aminobenzonitrile; 2-Amino-4-methoxy-5-bromobenzonitrile; Benzonitrile, 2-amino-5-bromo-4-methoxy-; 5-Bromo-4-methoxy-2-aminobenzonitrile; 2-Amino-5-bromo-4-methoxy-benzonitrile; 1173713-05-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-4-Methoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.