Description

N,N'-Bis[(tert-Butyloxy)Carbonyl]-L-Cystine Dimethyl Ester is a high-purity, protected derivative of the amino acid L-cystine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for researchers and manufacturers who require precise control over disulfide bond formation and side-chain protection during complex organic synthesis. It is primarily utilized in the development of peptide-based active pharmaceutical ingredients (APIs), biochemical research, and as a key building block in medicinal chemistry.

Application

• Peptide Synthesis Building Block: A crucial protected intermediate for the solid-phase and solution-phase synthesis of peptides containing cystine or cysteine residues.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based therapeutics, including hormones, enzyme inhibitors, and novel drug candidates.
• Bioconjugation Chemistry: Serves as a starting material for creating cross-linkers or modifying biomolecules where controlled disulfide bond formation is required.
• Biochemical Research: Employed in studies of protein folding, structure-activity relationships (SAR), and the synthesis of labeled compounds for analytical purposes.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	N,N'-Bis[(tert-Butyloxy)Carbonyl]-L-Cystine Dimethyl Ester
CAS No.	1173670-56-8
Molecular Formula	C22H38N2O10S2
Molecular Weight	554.67 g/mol
Synonyms	Boc-Cystine(OMe)-Boc; Di-Boc-L-Cystine Dimethyl Ester; L-Cystine, N,N'-bis[(1,1-dimethylethoxy)carbonyl]-, dimethyl ester; Boc-Cys(OMe)-Cys(OMe)-Boc; N,N'-Di-Boc-L-cystine dimethyl ester; (2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-{[(tert-butoxy)carbonyl]amino}propanoate); Boc-L-Cystine(OMe)-OH dimethyl ester
EINECS	Contact for details

Quality Control

Our N,N'-Bis[(tert-Butyloxy)Carbonyl]-L-Cystine Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.