Description

2-Bromo-4-Fluoro-1-((E)-2-Nitrovinyl)Benzene is a specialized aromatic building block featuring a bromo-fluoro substitution pattern and a reactive nitrovinyl functional group. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the bromo-fluoro-phenyl core provides specific biological activity and stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs or semiconductors, due to its electron-withdrawing nitrovinyl group.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck) to create more complex biaryl structures.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Ligand and Catalyst Development: Useful for constructing novel chelating ligands or organocatalysts in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-4-Fluoro-1-((E)-2-Nitrovinyl)Benzene
CAS No.	1173360-91-2
Molecular Formula	C8H5BrFNO2
Molecular Weight	246.04 g/mol
Synonyms	1-Bromo-4-fluoro-2-[(E)-2-nitroethenyl]benzene; (E)-2-Bromo-4-fluoro-1-(2-nitrovinyl)benzene; 2-Bromo-4-fluoro-β-nitrostyrene; 4-Fluoro-2-bromo-β-nitrostyrene; Benzene, 2-bromo-4-fluoro-1-[(E)-2-nitroethenyl]-; (E)-1-Bromo-4-fluoro-2-(2-nitrovinyl)benzene; 2-Bromo-4-fluoro-1-(2-nitrovinyl)benzene; (E)-2-Bromo-4-fluoro-β-nitrostyrene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-1-((E)-2-Nitrovinyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.