Description

1,4-Butanediamine-13C4, Putrescine-13C4 is a stable isotope-labeled analog of the biogenic amine putrescine, where all four carbon atoms are replaced with the 13C isotope. This compound is essential as a high-purity internal standard and tracer in quantitative mass spectrometry-based metabolomics and biomedical research. It is primarily used by analytical laboratories, pharmaceutical R&D departments, and academic research institutions engaged in biomarker discovery, metabolic pathway analysis, and pharmacokinetic studies.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the accurate quantification of endogenous putrescine levels in complex biological matrices like plasma, urine, and tissue extracts.
• Metabolomics & Biomarker Research: Used as a stable isotope tracer to elucidate polyamine biosynthesis and catabolism pathways, aiding in the study of diseases such as cancer and neurological disorders.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetic (DMPK) studies to track the fate of drug candidates and their interaction with polyamine systems.
• Clinical Diagnostics: Facilitates the development of robust LC-MS/MS assays for clinical testing, ensuring high accuracy and reproducibility in measuring polyamine-related biomarkers.
• Food & Nutritional Science: Applied in research to analyze polyamine content in foodstuffs and to study their role in nutrition and gut health.
• Quality Control & Method Validation: Essential for validating analytical methods in compliance with guidelines like ICH Q2(R1), ensuring specificity, accuracy, and precision.

Basic Information

Product Name	1,4-Butanediamine-13C4, Putrescine-13C4
CAS No.	1173023-66-9
Molecular Formula	13C4H12N2
Molecular Weight	92.12 (based on 13C)
Synonyms	Putrescine-13C4; 1,4-Diaminobutane-13C4; Tetramethylenediamine-13C4; Butane-1,4-diamine-13C4; 1,4-Butylenediamine-13C4; 13C4-Labeled Putrescine; [13C4]-Putrescine; Stable Isotope-Labeled Putrescine
EINECS	Contact for details

Quality Control

Our 1,4-Butanediamine-13C4 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation. We support GMP/GLP-compliant documentation for regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the product should be handled in a dry atmosphere and the container kept sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.