Description

Hexadecanoic-13,13,14,14,15,15,16,16,16-D9 Acid is a high-purity, isotopically labeled derivative of palmitic acid, where nine hydrogen atoms on the terminal methyl group are replaced with deuterium (D). This compound is essential for advanced analytical research, providing a stable, non-radioactive tracer for precise metabolic and pharmacokinetic studies. It is primarily used by researchers and scientists in pharmaceutical development, biochemistry, and nutritional science who require the highest standards of isotopic purity and chemical stability for their investigative work.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference in GC-MS and LC-MS analyses for accurate measurement of endogenous palmitic acid levels in complex biological matrices.
• Metabolic Pathway Tracing: Used in stable isotope labeling experiments (SIL) to elucidate lipid metabolism, fatty acid oxidation, and biosynthetic pathways in cell cultures, tissues, and whole organisms.
• Drug Metabolism & Pharmacokinetics (DMPK): Enables precise tracking of drug candidates that are palmitoylated or that interact with fatty acid pathways, aiding in ADME studies.
• Nutritional & Biomedical Research: Facilitates studies on dietary fat absorption, obesity, diabetes, and other metabolic disorders by allowing researchers to distinguish administered fatty acids from endogenous pools.
• Synthesis of Labeled Compounds: Acts as a key synthetic intermediate for preparing other deuterium-labeled lipids, surfactants, or bioactive molecules.

Basic Information

Product Name	Hexadecanoic-13,13,14,14,15,15,16,16,16-D9 Acid
CAS No.	1173022-49-5
Molecular Formula	C16H23D9O2
Molecular Weight	273.50 g/mol (approx.)
Synonyms	Palmitic Acid-d9; Hexadecanoic Acid-d9; n-Hexadecanoic-16,16,16-d3 Acid (common misnomer, full labeling specified); Deuterated Palmitic Acid; [13,13,14,14,15,15,16,16,16-2H9]Hexadecanoic Acid; Isotopic Labeled C16:0 Fatty Acid; 16,16,16-Trideuteriohexadecanoic Acid (incomplete labeling); (D9)Palmitic Acid
EINECS	Contact for details

Quality Control

Every batch of our isotopically labeled chemicals is produced and verified under a strict quality management system. Certificates of Analysis (COA) are provided, detailing key parameters such as isotopic purity (e.g., ≥98 atom % D), chemical purity (by GC or HPLC), and identity confirmation (by NMR, MS). We adhere to relevant industry standards for high-purity reference materials to ensure data integrity and reproducibility in your research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98 atom % D
Chemical Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.