Description

Flubendazole D3 is a deuterium-labeled internal standard of the broad-spectrum anthelmintic agent, flubendazole, essential for precise quantitative analysis in complex matrices. This stable isotope-labeled compound is critical for ensuring accuracy and reliability in pharmacokinetic, metabolic, and residue studies, providing unmatched specificity in mass spectrometry-based assays. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in advanced analytical method development and validation.

Application

• Internal standard for the quantitative LC-MS/MS analysis of flubendazole and its metabolites in biological samples (e.g., plasma, tissue).
• Use in pharmacokinetic and bioavailability studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Critical component in the development and validation of regulatory-compliant analytical methods for veterinary drug residue testing.
• Support for metabolic pathway identification and profiling studies in preclinical and clinical research.
• Calibration standard for ensuring data integrity and meeting Good Laboratory Practice (GLP) requirements in bioanalytical assays.
• Reference material for quality control and assurance in the production and analysis of flubendazole-based pharmaceutical formulations.

Basic Information

Item	Detail
Product Name	Flubendazole D3
CAS No.	1173021-08-3
Molecular Formula	C16H9D3FN2O3
Molecular Weight	316.31 g/mol
Synonyms	Flubendazole-methyl-d3; [Methyl-d3]-Flubendazole; 5(6)-[4-Fluorobenzoyl]-1H-benzimidazol-2-yl]carbamic acid methyl-d3 ester; Deuterated Flubendazole; Flubendazole Internal Standard; Flubendazole-d3; (5-Benzoyl-1H-benzimidazol-2-yl)carbamic Acid Methyl-d3 Ester
EINECS	Contact for details

Quality Control

Our Flubendazole D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and confirmation of structure. We adhere to standards relevant to reference material production, ensuring reliability for your most demanding GLP and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.