Description

Doxylaminephenyl-D5 is a deuterated analog of doxylamine, a compound of significant interest in pharmaceutical research and development. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical data. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and analytical chemistry sectors for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal standard for the quantitative analysis of doxylamine via LC-MS/MS and GC-MS.
• Metabolite profiling and pharmacokinetic studies in drug development.
• Use in bioanalytical method development and validation for regulatory submissions.
• Quality control and assurance testing in pharmaceutical manufacturing.
• Research into drug metabolism and disposition mechanisms.
• Forensic and clinical toxicology analysis.
• Stable isotope dilution analysis for high-precision measurements.
• Use in environmental fate studies of pharmaceutical compounds.

Basic Information

Item	Details
Product Name	Doxylaminephenyl-D5
CAS No.	1173020-59-1
Molecular Formula	C17H17D5N2O
Molecular Weight	279.39 g/mol
Synonyms	Doxylamine-d5; Doxylamine (phenyl-d5); 2-[α-[2-(Dimethylamino)ethoxy]-α-methylbenzyl]pyridine (phenyl-d5); N,N-Dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine (phenyl-d5); Doxylamine (phenyl ring-d5); Doxylamine D5; Doxylamine Internal Standard; Doxylamine Stable Isotope
EINECS	Contact for details

Quality Control

Our Doxylaminephenyl-D5 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, suitable for the most demanding analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent content, verified by advanced techniques including NMR and mass spectrometry. We adhere to relevant industry standards to support research and development under GLP and GMP frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the material should be handled in a dry environment and the container kept tightly sealed after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.