Description

n-Desethyl Oxybutynin-D5 HCl is a high-purity, stable isotope-labeled internal standard critical for advanced analytical chemistry. This deuterated compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily utilized by pharmaceutical research and development laboratories, contract research organizations (CROs), and quality control facilities engaged in bioanalytical method development and validation.

Application

• Bioanalytical Method Development: Serves as a critical internal standard for the precise quantification of oxybutynin and its metabolites in complex biological matrices (e.g., plasma, urine) using LC-MS/MS.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) profiles in preclinical and clinical research.
• Pharmaceutical Quality Control: Used in validated analytical methods to ensure batch-to-batch consistency and purity of active pharmaceutical ingredients (APIs) and finished drug products.
• Forensic and Doping Control Analysis: Provides a reliable reference for the confirmatory analysis of oxybutynin in forensic toxicology and anti-doping programs.
• Stable Isotope Dilution Assays: Fundamental component in high-precision assays that correct for analyte loss during sample preparation and instrument variability.

Basic Information

Product Name	n-Desethyl Oxybutynin-D5 HCl
CAS No.	1173018-49-9
Molecular Formula	C20H26D5NO3•HCl
Molecular Weight	~367.95 g/mol
Synonyms	4-(Diethylamino)but-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate-d5 Hydrochloride; Oxybutynin N-Desethyl-d5 Hydrochloride; Oxybutynin Impurity D-d5 HCl; Deuterated Oxybutynin Metabolite Standard; 2-Cyclohexyl-2-hydroxy-2-phenylacetic Acid 4-(Diethylamino)-2-butynyl Ester-d5 Hydrochloride; Ditropan Metabolite-d5 HCl
EINECS	Contact for details

Quality Control

Every batch of n-Desethyl Oxybutynin-D5 HCl is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support your regulatory submissions, including Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation via NMR and MS. Our standards are developed to meet the rigorous demands of GMP/GLP-compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (Deuterium Enrichment)	≥98.0 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.