Description

3-(3-Fluoro-4-Methoxy-Benzyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzyl-piperidine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing central nervous system (CNS) and other therapeutic agents. The product is supplied as a hydrochloride salt to ensure enhanced stability and handling properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Fine Chemical Synthesis: Serves as a precursor for more complex molecules in custom synthesis and contract manufacturing.
• API Development: Employed in the development and scale-up processes for potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Used as a reference standard or ligand in biochemical assays and pharmacological studies.

Basic Information

Product Name	3-(3-Fluoro-4-Methoxy-Benzyl)-Piperidine Hydrochloride
CAS No.	1172742-77-6
Molecular Formula	C14H20FNO2 • HCl
Molecular Weight	289.78 g/mol
Synonyms	3-[(3-Fluoro-4-methoxyphenyl)methyl]piperidine hydrochloride; 1-(3-Fluoro-4-methoxybenzyl)piperidine-3-carboxylic acid hydrochloride (isomer); 3-(3-Fluoro-4-methoxybenzyl)piperidine HCl; Piperidine, 3-[(3-fluoro-4-methoxyphenyl)methyl]-, hydrochloride (1:1); 1172742-77-6; 3-Fluoro-4-methoxybenzylpiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-4-Methoxy-Benzyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.