Description

2-(Trifluoromethyl)Cyclopropan-1-Amine Hydrochloride is a high-purity, organofluorine building block essential for advanced pharmaceutical and agrochemical synthesis. This compound is valued for its unique cyclopropane ring and trifluoromethyl group, which are critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily sought by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced herbicide and insecticide molecules, where the trifluoromethyl group enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique fluorinated properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	2-(Trifluoromethyl)Cyclopropan-1-Amine Hydrochloride
CAS No.	1172072-62-6
Molecular Formula	C4H7ClF3N
Molecular Weight	161.55 g/mol
Synonyms	1-Amino-2-(trifluoromethyl)cyclopropane hydrochloride; (1R,2S)-rel-2-(Trifluoromethyl)cyclopropanamine hydrochloride; 2-(Trifluoromethyl)cyclopropanamine HCl; 2-Trifluoromethylcyclopropylamine hydrochloride; (1-Amino-2-trifluoromethyl-cyclopropyl)-hydrochloride; trans-2-(Trifluoromethyl)cyclopropan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Cyclopropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.