Description

1-(2,2-Difluoro-Ethyl)-3-Nitro-1H-Pyrazole is a specialized fluorinated pyrazole derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroethyl and nitro substituents, enabling precise molecular construction for demanding applications. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its fluorinated structure for enhanced bioactivity and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced materials with tailored properties.
• Ligand Synthesis: Employed in the creation of complex ligands for catalysis and coordination chemistry, useful in asymmetric synthesis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the behavior of fluorine-containing heterocycles in synthetic pathways.

Basic Information

Product Name	1-(2,2-Difluoro-Ethyl)-3-Nitro-1H-Pyrazole
CAS No.	1171087-45-8
Molecular Formula	C5H5F2N3O2
Molecular Weight	177.11 g/mol
Synonyms	3-Nitro-1-(2,2-difluoroethyl)-1H-pyrazole; 1-(2,2-Difluoroethyl)-3-nitropyrazole; 1H-Pyrazole, 1-(2,2-difluoroethyl)-3-nitro-; 1171087-45-8; 1-(2,2-Difluoroethyl)-3-nitro-1H-pyrazole; 3-Nitro-1-(2,2-difluoroethyl)pyrazole
EINECS	Contact for details

Quality Control

Our 1-(2,2-Difluoro-Ethyl)-3-Nitro-1H-Pyrazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.