Description

3-(3-(Trifluoromethyl)Benzyl)Piperidine Hydrochloride is a high-purity, fluorinated piperidine derivative used as a critical building block in advanced organic synthesis. Its value lies in the unique trifluoromethylbenzyl moiety, which is instrumental in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for creating advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and liquid crystals.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Benzyl)Piperidine Hydrochloride
CAS No.	1170475-37-2
Molecular Formula	C13H16ClF3N
Molecular Weight	278.72 g/mol
Synonyms	3-[(3-(Trifluoromethyl)phenyl)methyl]piperidine hydrochloride; 1-[3-(Trifluoromethyl)benzyl]piperidin-3-amine hydrochloride; Piperidine, 3-[[3-(trifluoromethyl)phenyl]methyl]-, hydrochloride (1:1); 3-(3-(Trifluoromethyl)benzyl)piperidine HCl; 1170475-37-2
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Benzyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions if opened for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.