Description

n-((1-Benzyl-4-Hydroxypiperidin-4-Yl)Methyl)-2-Chloroacetamide is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-based molecular scaffold. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and receptor-based therapeutic areas. Pharmaceutical R&D departments and fine chemical manufacturers need this precise building block to ensure the integrity and efficacy of their final drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel central nervous system (CNS) active drugs and receptor modulators.
• API Synthesis: Used in multi-step organic synthesis for constructing complex molecular architectures in active pharmaceutical ingredients.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material science and agrochemical research.
• Biochemical Tool Compound: Potential use in developing biochemical probes for studying enzyme inhibition or cellular signaling pathways.

Basic Information

Product Name	n-((1-Benzyl-4-Hydroxypiperidin-4-Yl)Methyl)-2-Chloroacetamide
CAS No.	1169699-63-1
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	2-Chloro-N-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]acetamide; 1-Benzyl-4-[(2-chloroacetamido)methyl]-4-hydroxypiperidine; N-[(1-Benzyl-4-hydroxypiperidin-4-yl)methyl]-2-chloroacetamide; 1169699-63-1; 2-Chloro-N-((1-benzyl-4-hydroxypiperidin-4-yl)methyl)acetamide; (1-Benzyl-4-hydroxypiperidin-4-yl)methyl 2-chloroacetamide; Acetamide, 2-chloro-N-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]-
EINECS	Contact for details

Quality Control

Our n-((1-Benzyl-4-Hydroxypiperidin-4-Yl)Methyl)-2-Chloroacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.