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11-Dicyclohexylphosphino-12-(2-Methoxyphenyl)-9,10-Ethenoanthracene Dichloromethane Adduct, Min. 98% o-Meo Kitphos CAS NO 1166994-78-0
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CAS No.:1166994-78-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
11-Dicyclohexylphosphino-12-(2-Methoxyphenyl)-9,10-Ethenoanthracene Dichloromethane Adduct, Min. 98% o-Meo Kitphos is a highly specialized, air-stable organophosphorus ligand, specifically designed for demanding catalytic transformations. Its core value lies in enabling highly efficient and selective cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, which are critical for constructing complex molecules in pharmaceutical and advanced material synthesis. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance ligands to optimize catalytic processes and scale up production.
Application
- Pharmaceutical Intermediate Synthesis: As a key ligand in palladium-catalyzed cross-coupling reactions for constructing biaryl and heteroaryl motifs in active pharmaceutical ingredients (APIs).
- Agrochemical Manufacturing: Used in the catalytic synthesis of complex molecules for novel herbicides, fungicides, and insecticides.
- Material Science Research: Facilitating the synthesis of conjugated polymers and organic electronic materials through efficient C-C and C-N bond formation.
- Process Chemistry & Scale-Up: Valued for its stability and performance in moving reactions from laboratory scale to pilot plant and commercial production.
- Academic & Industrial R&D: A critical tool for methodological development in organic synthesis and catalysis research.
- Fine Chemical Production: Enabling the synthesis of complex, high-value specialty chemicals and flavors & fragrances.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 11-Dicyclohexylphosphino-12-(2-Methoxyphenyl)-9,10-Ethenoanthracene Dichloromethane Adduct, Min. 98% o-Meo Kitphos |
| CAS No. | 1166994-78-0 |
| Molecular Formula | C37H39OP • CH2Cl2 |
| Molecular Weight | Approx. 617.57 g/mol (ligand + adduct) |
| Synonyms | o-Meo Kitphos; 2-Methoxyphenyl Kitphos; (2-Methoxyphenyl)Kitphos; 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-dihydro-9,10-[1,2]benzenoanthracene Dichloromethane Adduct; Kitphos(o-OMe); Dicyclohexyl(2-methoxyphenyl)phosphine-anthracene adduct; Buchwald Ligand o-MeO-Kitphos |
| EINECS | Contact for details |
Quality Control
Every batch of o-Meo Kitphos is manufactured and tested under strict quality management systems to ensure consistent, high-performance material for catalytic applications. We guarantee a minimum purity of 98%, verified by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and solvent content is provided with each shipment to support your quality and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials. The dichloromethane adduct form enhances stability for handling and storage.
Specification
| Item | Specification |
|---|---|
| Appearance | Yellow to orange solid |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | Min. 98.0% |
| Solvent Content (Residue on Evaporation) | Dichloromethane: 10-15% w/w |
| Water Content (KF) | Max. 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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