Description

3-Amino-2-Bromobenzonitrile is a high-purity aromatic nitrile building block featuring both amino and bromo substituents, making it a versatile intermediate for advanced synthesis. Its molecular structure is critical for constructing complex heterocycles and functionalized aromatic systems in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in creating new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized colorants and functional dyes due to its amino and cyano groups.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, or Sonogashira couplings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	3-Amino-2-Bromobenzonitrile
CAS No.	1166988-09-5
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	2-Bromo-3-aminobenzonitrile; 3-Amino-2-bromobenzene carbonitrile; 2-Bromo-3-cyanoaniline; Benzonitrile, 3-amino-2-bromo-; 3-Amino-2-bromophenyl cyanide; 2-Bromo-3-aminophenyl cyanide; (3-Amino-2-bromophenyl) cyanide
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Bromobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.