Description

2-Fluoro-4-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with improved efficacy.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand & Catalyst Development: Useful in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-4-Methylphenylboronic Acid Pinacol Ester
CAS No.	1165936-03-7
Molecular Formula	C₁₃H₁₈BFO₂
Molecular Weight	236.09 g/mol
Synonyms	2-Fluoro-4-methylbenzeneboronic acid pinacol ester; (2-Fluoro-4-methylphenyl)boronic acid pinacol ester; 4-Methyl-2-fluorophenylboronic acid pinacol ester; 2-Fluoro-p-tolylboronic acid pinacol ester; Pinacol (2-fluoro-4-methylphenyl)boronate; B-(2-Fluoro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1165936-03-7
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.