Description

1-Bromo-2-Ethoxy-4-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry for introducing the trifluoromethoxy pharmacophore.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the benzene core provides structural diversity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Functional Material Research: Employed in academic and industrial labs for developing novel polymers and advanced materials with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-Bromo-2-Ethoxy-4-(Trifluoromethoxy)Benzene
CAS No.	1162261-92-8
Molecular Formula	C9H8BrF3O2
Molecular Weight	285.06 g/mol
Synonyms	2-Bromo-1-ethoxy-4-(trifluoromethoxy)benzene; 4-Bromo-3-ethoxy-1-(trifluoromethoxy)benzene; 1-Bromo-2-ethoxy-4-(trifluoromethoxy)benzene; Benzene, 1-bromo-2-ethoxy-4-(trifluoromethoxy)-; 2-Ethoxy-4-(trifluoromethoxy)bromobenzene; 4-(Trifluoromethoxy)-2-ethoxybromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Ethoxy-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.