Description

2-(Allyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic intermediate designed for advanced chemical synthesis. This compound is valued for its unique molecular architecture, which incorporates reactive bromo, allyloxy, and trifluoromethoxy functional groups on a benzene ring, enabling precise derivatization. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the trifluoromethoxy group for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its aromatic core and fluorine content contribute to desired electronic and optical properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Polymer Modification: The allyloxy group allows for incorporation into polymer backbones or side chains via radical or thermal processes, creating specialty polymers with tailored functionalities.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-(Allyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene
CAS No.	1162257-62-6
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	1-Bromo-2-(allyloxy)-4-(trifluoromethoxy)benzene; 2-Allyloxy-1-bromo-4-trifluoromethoxybenzene; 4-Bromo-3-(trifluoromethoxy)phenyl allyl ether; Allyl 4-bromo-3-(trifluoromethoxy)phenyl ether; Benzene, 1-bromo-2-(2-propen-1-yloxy)-4-(trifluoromethoxy)-; 2-Bromo-1-(allyloxy)-4-(trifluoromethoxy)benzene (isomer)
EINECS	Contact for details

Quality Control

Every batch of 2-(Allyloxy)-1-Bromo-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.