Description

4-Propoxy-3-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound widely used as a key building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the unique properties of the trifluoromethyl moiety.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand & Catalyst Development: Employed in the preparation of novel boron-containing ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new chemical entities and optimizing synthetic routes.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring bespoke boronic acid derivatives.

Basic Information

Product Name	4-Propoxy-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1162257-45-5
Molecular Formula	C10H12BF3O3
Molecular Weight	248.01 g/mol
Synonyms	[4-(Propoxy)-3-(trifluoromethyl)phenyl]boronic acid; 3-Trifluoromethyl-4-propoxybenzeneboronic acid; 4-Propoxy-3-trifluoromethylbenzeneboronic acid; (4-Propoxy-3-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[4-(propoxy)-3-(trifluoromethyl)phenyl]-; 4-n-Propoxy-3-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Propoxy-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.