Description

Pyrrolidine-2-Carboxylic Acid (4-Chloro-Phenyl)-Amide is a high-purity, specialized organic compound designed for advanced chemical synthesis and pharmaceutical research. This molecule serves as a critical chiral building block and intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and functional groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Scaffold: Used to construct constrained peptide analogs and protease inhibitors by incorporating the pyrrolidine carboxylic acid amide motif.
• Ligand Synthesis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Agrochemical Research: Employed as an intermediate in the synthesis of novel herbicides, fungicides, and plant growth regulators with specific biological activity.
• Material Science: Potential building block for advanced polymers and functional materials requiring specific amide linkages and aromatic chlorination.

Basic Information

Product Name	Pyrrolidine-2-Carboxylic Acid (4-Chloro-Phenyl)-Amide
CAS No.	1161720-69-9
Molecular Formula	C11H13ClN2O
Molecular Weight	224.69 g/mol
Synonyms	(S)-1-[(4-Chlorophenyl)carbamoyl]pyrrolidine-2-carboxylic acid; L-Proline, N-[(4-chlorophenyl)carbamoyl]-; 4-Chloro-N-[(2S)-2-pyrrolidinecarbonyl]aniline; (S)-Pyrrolidine-2-carboxylic acid (4-chloro-phenyl)-amide; (2S)-1-[(4-Chlorophenyl)carbamoyl]pyrrolidine-2-carboxylic acid; 4-Chloro-N-[(2S)-pyrrolidine-2-carbonyl]aniline; Proline, N-(4-chloroanilino)carbonyl-
EINECS	Contact for details

Quality Control

Our Pyrrolidine-2-Carboxylic Acid (4-Chloro-Phenyl)-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.