Description

5-Iodo-2-(Methylthio)Benzonitrile is a high-purity, specialized organic building block featuring a benzonitrile core substituted with iodine and a methylthio group. This compound is valued for its unique reactivity profile, serving as a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including potential active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various disease states.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides, leveraging its halogen and sulfur functionalities.
• Material Science Research: Serves as a precursor for the synthesis of functional organic materials, including liquid crystals and organic electronic components.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-Iodo-2-(Methylthio)Benzonitrile
CAS No.	1161499-58-6
Molecular Formula	C8H6INS
Molecular Weight	275.11 g/mol
Synonyms	2-(Methylthio)-5-iodobenzonitrile; 5-Iodo-2-methylthiobenzonitrile; Benzonitrile, 5-iodo-2-(methylthio)-; 2-Methylsulfanyl-5-iodobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Iodo-2-(Methylthio)Benzonitrile is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.