Description

Benzeneacetic Acid, 2-Fluoro-4-Nitro-, Ethyl Ester is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the strategic placement of fluorine and nitro groups enables precise tuning of biological activity and physicochemical properties. It is primarily sought by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Chemical Biology Probes: Utilized as a scaffold for synthesizing fluorescent tags and molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	Benzeneacetic Acid, 2-Fluoro-4-Nitro-, Ethyl Ester
CAS No.	1160623-38-0
Molecular Formula	C10H10FNO4
Molecular Weight	227.19 g/mol
Synonyms	Ethyl 2-Fluoro-4-nitrophenylacetate; 2-(2-Fluoro-4-nitrophenyl)acetic Acid Ethyl Ester; 2-Fluoro-4-nitrophenylacetic Acid Ethyl Ester; (2-Fluoro-4-nitrophenyl)acetic Acid Ethyl Ester; Ethyl (2-Fluoro-4-nitrophenyl)acetate; 1160623-38-0; Benzeneacetic acid, 2-fluoro-4-nitro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 2-Fluoro-4-Nitro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP and ISO standards for intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.