Description

3-Bromo-5-Chloro-2-Iodobenzonitrile is a high-purity, multi-halogenated benzonitrile derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides by introducing halogenated aromatic motifs into lead structures.
• Material Science Building Block: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing halogen substituents.
• Cross-Coupling Reactions: Serves as an excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl and conjugated systems.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Iodobenzonitrile
CAS No.	1160574-37-7
Molecular Formula	C7H2BrClIN
Molecular Weight	356.36 g/mol
Synonyms	2-Iodo-3-bromo-5-chlorobenzonitrile; 3-Bromo-5-chloro-2-iodobenzonitrile; Benzonitrile, 3-bromo-5-chloro-2-iodo-; 2-Cyano-6-bromo-4-chloro-1-iodobenzene; 5-Chloro-3-bromo-2-iodobenzonitrile; 2-Iodo-5-chloro-3-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-2-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.