Description

1-Bromo-5-Chloro-2,3-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Fluorinated core structure for electronic materials used in displays and optoelectronic devices.
• Polymer Chemistry: Monomer for specialty polymers and functional materials requiring halogenated aromatic units.
• Cross-Coupling Reactions: Versatile substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions in medicinal chemistry.
• Chemical Research: Valuable reagent for academic and industrial research in organofluorine chemistry and material science.

Basic Information

Product Name	1-Bromo-5-Chloro-2,3-Difluorobenzene
CAS No.	1160573-26-1
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2,3-Difluoro-5-chloro-1-bromobenzene; 5-Chloro-2,3-difluorobromobenzene; 1-Bromo-5-chloro-2,3-difluorobenzol; Benzene, 1-bromo-5-chloro-2,3-difluoro-; Bromochlorodifluorobenzene (mixed isomer designation); BCFB (abbreviation); 1160573-26-1 (CAS registry)
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Chloro-2,3-Difluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard grade meets typical requirements for advanced synthetic applications, with purity specifications available upon request. Custom synthesis and purification to meet specific project requirements (e.g., >99% HPLC, low metal content) are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.