Description

(3,4-Dichloro-2-Fluorophenyl)Boronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecules through cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides by introducing the (3,4-dichloro-2-fluorophenyl) moiety into target molecules.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling: The quintessential application, acting as a boronic acid coupling partner with aryl/vinyl halides to form biaryl and other C-C bonds with high efficiency.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological systems and mechanisms.

Basic Information

Product Name	(3,4-Dichloro-2-Fluorophenyl)Boronic Acid
CAS No.	1160561-29-4
Molecular Formula	C6H4BCl2FO2
Molecular Weight	208.82 g/mol
Synonyms	(3,4-Dichloro-2-fluorophenyl)boronic acid; 2-Fluoro-3,4-dichlorophenylboronic acid; (3,4-Dichloro-2-fluorophenyl)boronic acid pinacol ester (protected form); B-(3,4-Dichloro-2-fluorophenyl)boronic acid; 3,4-Dichloro-2-fluorobenzeneboronic acid; 1160561-29-4; Boronic acid, B-(3,4-dichloro-2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our (3,4-Dichloro-2-Fluorophenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive cross-coupling reactions. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.