Description

2,4-Dichloro-3-Fluorophenylboronic Acid is a high-purity, multi-halogenated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique halogen substitution pattern, which enables precise cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with specific halogenated aromatic backbones.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	2,4-Dichloro-3-Fluorophenylboronic Acid
CAS No.	1160561-27-2
Molecular Formula	C6H4BCl2FO2
Molecular Weight	208.82 g/mol
Synonyms	(2,4-Dichloro-3-fluorophenyl)boronic acid; 2,4-Dichloro-3-fluorobenzeneboronic acid; B-(2,4-Dichloro-3-fluorophenyl)boronic acid; 3-Fluoro-2,4-dichlorophenylboronic acid; 1160561-27-2; Boronic acid, B-(2,4-dichloro-3-fluorophenyl)-; AKOS005258023
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.