Description

2'-(Dicyclohexylphosphino)-6-Methoxy-N,n-Dimethylbiphenyl-2-Amine is a specialized, high-value organophosphorus ligand used in advanced catalytic transformations. Its primary value lies in enabling highly efficient and selective cross-coupling reactions, which are critical for constructing complex molecular architectures in fine chemical synthesis. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require robust and tunable catalysts for challenging bond-forming steps.

Application

• Pharmaceutical Intermediate Synthesis: As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) for constructing active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the catalytic synthesis of complex heterocyclic compounds that serve as advanced herbicides, fungicides, and insecticides.
• Material Science Research: Facilitates the synthesis of conjugated polymers and organic electronic materials through efficient C-C and C-N bond formation.
• Catalyst Development: Serves as a precursor or component in the development of novel homogeneous catalysts for asymmetric synthesis and other specialized chemical processes.
• Academic & Industrial R&D: A vital tool for methodology development in organic synthesis, enabling new routes to complex molecules in research laboratories.

Basic Information

Product Name	2'-(Dicyclohexylphosphino)-6-Methoxy-N,n-Dimethylbiphenyl-2-Amine
CAS No.	1160556-61-5
Molecular Formula	C27H38NOP
Molecular Weight	423.57 g/mol
Synonyms	DavePhos; 2-(Dicyclohexylphosphino)-2'-(N,N-dimethylamino)-6-methoxybiphenyl; 2'-(Dicyclohexylphosphino)-N,N-dimethyl-6-methoxy-[1,1'-biphenyl]-2-amine; 2-(Dicyclohexylphosphino)-2'-(dimethylamino)-6-methoxybiphenyl; [2'-(Dimethylamino)-6-methoxy[1,1'-biphenyl]-2-yl]dicyclohexylphosphine; Dicyclohexyl(6'-methoxy-2'-(N,N-dimethylamino)biphenyl-2-yl)phosphine
EINECS	Contact for details

Quality Control

Our production of 2'-(Dicyclohexylphosphino)-6-Methoxy-N,n-Dimethylbiphenyl-2-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including HPLC for purity assessment and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.