Description

1-Fluoro-2-Isopropoxybenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and an isopropoxy substituent on the benzene ring, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom can improve biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing components in electronic display materials and organic light-emitting diodes.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, altering thermal stability and chemical resistance.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form biaryl and other complex structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating specialized chemical libraries for screening.

Basic Information

Product Name	1-Fluoro-2-Isopropoxybenzene
CAS No.	1160293-58-2
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	2-Fluoro-1-isopropoxybenzene; 1-Isopropoxy-2-fluorobenzene; o-Fluorophenyl isopropyl ether; 2-Fluorophenyl isopropyl ether; (2-Fluorophenoxy)propane; Isopropyl 2-fluorophenyl ether; Benzene, 1-fluoro-2-(1-methylethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 1-Fluoro-2-Isopropoxybenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing, including GC, HPLC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.