Description

2-(3,4-Dimethoxyphenyl)Indane-2-Carbonitrile is a high-value, synthetically versatile organic intermediate characterized by its indane core and dimethoxyphenyl substituent. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries seeking to develop new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex polycyclic architectures.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products, leveraging its aromatic and nitrile functionality.
• Material Science: Used in the research and development of organic electronic materials, such as charge-transport molecules or ligands for metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies in organic chemistry, including cross-coupling and cyanation reactions.
• Ligand & Catalyst Development: The molecular scaffold can be modified to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Fluorescent Probe Synthesis: Acts as a starting material for constructing fluorophores and molecular probes used in bioimaging and diagnostics.

Basic Information

Product Name	2-(3,4-Dimethoxyphenyl)Indane-2-Carbonitrile
CAS No.	1160264-27-6
Molecular Formula	C18H17NO2
Molecular Weight	279.34 g/mol
Synonyms	2-(3,4-Dimethoxyphenyl)-2,3-dihydro-1H-indene-2-carbonitrile; 2-(3,4-Dimethoxyphenyl)indan-2-carbonitrile; 1H-Indene-2-carbonitrile, 2-(3,4-dimethoxyphenyl)-2,3-dihydro-; 2-(3,4-Dimethoxyphenyl)-1-indanecarbonitrile; (3,4-Dimethoxyphenyl)(1-cyano-2,3-dihydro-1H-inden-2-yl)methane
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethoxyphenyl)Indane-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.