Description

5-Oxohexyl Biotin is a high-purity, advanced biotin derivative designed for sophisticated bioconjugation and pharmaceutical research. This compound serves as a critical intermediate for the synthesis of biotinylated probes and targeted drug delivery systems, enabling precise biochemical interactions. It is essential for researchers and manufacturers in the fields of pharmaceutical development, diagnostic assay production, and advanced life science research.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing novel biotin-conjugated active pharmaceutical ingredients (APIs) and targeted therapeutics.
• Diagnostic Reagents: Used in the development of biotin-streptavidin based immunoassays, ELISA kits, and biosensors for high-sensitivity detection.
• Bioconjugation & Labeling: Facilitates the site-specific labeling of antibodies, proteins, peptides, and oligonucleotides for research and diagnostic applications.
• Drug Delivery Systems: Incorporated into ligand-targeted drug carriers, such as liposomes and nanoparticles, for enhanced cellular uptake.
• Biochemical Research: Serves as a vital tool in proteomics, cellular imaging, and affinity purification studies.
• Precision Medicine: Enables the development of companion diagnostics and theranostic agents.

Basic Information

Product Name	5-Oxohexyl Biotin
CAS No.	1160188-05-5
Molecular Formula	C16H26N2O4S
Molecular Weight	342.45 g/mol
Synonyms	5-Oxohexyl-D-biotin; Biotin-6-hexanoic acid; (+)-Biotin-6-hexanoic acid; 6-[(+)-Biotinyl]hexanoic acid; 6-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid; D-Biotin-6-hexanoic acid; Biotinyl-6-aminocaproic acid; Biotin-C6-COOH
EINECS	Contact for details

Quality Control

Our 5-Oxohexyl Biotin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.