Description

Tianeptine Metabolite Mc5 Methyl Ester is a key synthetic intermediate and reference standard in pharmaceutical research and development. This compound is of significant value for analytical and metabolic studies related to the antidepressant tianeptine, enabling precise quantification and pathway elucidation. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuropharmacology, bioanalytical method development, and impurity profiling.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quantification of tianeptine and its metabolites in biological matrices during pharmacokinetic and bioequivalence studies.
• Metabolic Pathway Research: Used as a definitive standard to identify and characterize the metabolic fate of tianeptine in preclinical and clinical research, aiding in drug safety and efficacy evaluations.
• Analytical Method Development: Essential for developing and validating high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and other analytical methods in quality control and research laboratories.
• Impurity Synthesis and Profiling: Employed as a starting material or intermediate for synthesizing related compounds required for impurity identification and control in active pharmaceutical ingredient (API) manufacturing.
• Preclinical Toxicology Studies: Utilized to prepare dosing solutions and as an analytical standard in safety assessment studies to understand metabolite-related toxicity.

Basic Information

Product Name	Tianeptine Metabolite Mc5 Methyl Ester
CAS No.	1159977-59-9
Molecular Formula	C22H25ClN2O4S
Molecular Weight	448.96 g/mol
Synonyms	MC 5 Methyl Ester; Tianeptine Metabolite MC5 Methyl Ester; 7-[(3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic Acid Methyl Ester; Methyl 7-[(3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate; Tianeptine Acid Metabolite Methyl Ester
EINECS	Contact for details

Quality Control

Our Tianeptine Metabolite Mc5 Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR, MS), purity assessment by HPLC, and control of specific impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade standards. We support our clients' regulatory needs with full documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.