Description

2,2-Diphenyl-2-(1-Boc-3-Pyrrolidinyl)Acetonitrile is a high-value, advanced pharmaceutical intermediate featuring a protected pyrrolidine scaffold. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical companies developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile, protected amine functionality.
• Protease Inhibitor Development: Acts as a precursor in the creation of inhibitors for various enzymatic targets.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke fine chemicals and reference standards.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	2,2-Diphenyl-2-(1-Boc-3-Pyrrolidinyl)Acetonitrile
CAS No.	1159977-31-7
Molecular Formula	C24H28N2O2
Molecular Weight	376.50 g/mol
Synonyms	1-Boc-3-cyano-3,3-diphenylpyrrolidine; tert-Butyl 3-cyano-3,3-diphenylpyrrolidine-1-carboxylate; 3-Cyano-3,3-diphenyl-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-cyano-3,3-diphenylpyrrolidine; 3,3-Diphenyl-1-Boc-3-cyanopyrrolidine; 2-(1-Boc-3-Pyrrolidinyl)-2,2-diphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 2,2-Diphenyl-2-(1-Boc-3-Pyrrolidinyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.