Description

2-Methyl-3-Fluoroanisole is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of a methoxy group and a fluorine atom on a methyl-substituted benzene ring, enabling precise modulation of electronic and steric properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display materials, improving charge transport and thermal stability.
• Organic Ligand Preparation: Employed in the manufacture of specialized ligands for catalysis, leveraging the electron-donating methoxy and electron-withdrawing fluoro groups for fine-tuning metal coordination.
• Fluorine-Containing Polymer Research: Acts as a monomer or modifier in the development of specialty polymers with enhanced chemical resistance and unique surface properties.
• Chemical Research & Development: A versatile building block for exploring novel reaction pathways and creating compound libraries in academic and industrial R&D settings.

Basic Information

Product Name	2-Methyl-3-Fluoroanisole
CAS No.	1159883-21-2
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	1-Fluoro-2-methoxy-6-methylbenzene; 3-Fluoro-2-methoxytoluene; 2-Methoxy-6-fluorotoluene; 6-Fluoro-o-cresol methyl ether; 2-Fluoro-6-methylanisole; o-Cresol, 6-fluoro-, methyl ether; Benzene, 1-fluoro-2-methoxy-6-methyl-
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-Fluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.10 g/cm³
Refractive Index (n20D)	~1.485

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.