Description

3-Amino-Alpha,Alpha,Alpha,2-Tetrafluoroanisole is a specialized fluorinated aniline derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the unique combination of an electron-donating amino group and electron-withdrawing fluorine atoms, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic display and lighting technologies.
• Polymer Modification: Serves as a monomer or functionalizing agent for engineering polymers with specific thermal and chemical resistance.
• Dye & Pigment Chemistry: Intermediate for synthesizing advanced fluorinated colorants with superior lightfastness and stability.
• Cross-Coupling Reactions: Valuable substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	3-Amino-Alpha,Alpha,Alpha,2-Tetrafluoroanisole
CAS No.	1159512-64-7
Molecular Formula	C8H7F4NO
Molecular Weight	209.14 g/mol
Synonyms	3-Amino-2,4,5,6-tetrafluoroanisole; 2,4,5,6-Tetrafluoro-3-methoxyaniline; 3-Methoxy-2,4,5,6-tetrafluoroaniline; 2,4,5,6-Tetrafluoro-3-aminoanisole; 3-Amino-2,4,5,6-tetrafluoromethoxybenzene; Anisole, 3-amino-2,4,5,6-tetrafluoro-; Benzene, 1-methoxy-2,4,5,6-tetrafluoro-3-amino-
EINECS	Contact for details

Quality Control

Our 3-Amino-Alpha,Alpha,Alpha,2-Tetrafluoroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.