Description

1-(Bromomethyl)-2-Fluoro-3-(Trifluoromethoxy)Benzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is critical for introducing a reactive benzyl bromide moiety adjacent to fluorine and trifluoromethoxy substituents, enabling precise molecular construction. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex molecules in drug discovery and development, particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromomethyl group is reactive in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Ligand & Catalyst Development: Useful for constructing sophisticated ligand frameworks in coordination chemistry and catalysis.
• Functional Polymer Monomer: Can be incorporated into polymer backbones to impart specific properties like chemical resistance or modified solubility.

Basic Information

Product Name	1-(Bromomethyl)-2-Fluoro-3-(Trifluoromethoxy)Benzene
CAS No.	1159512-59-0
Molecular Formula	C9H5BrF4O
Molecular Weight	285.04 g/mol
Synonyms	2-Fluoro-3-(trifluoromethoxy)benzyl bromide; α-Bromo-2-fluoro-3-(trifluoromethoxy)toluene; (2-Fluoro-3-(trifluoromethoxy)phenyl)methyl bromide; 2-Fluoro-α-(bromomethyl)-3-(trifluoromethoxy)benzene; 1-Bromomethyl-2-fluoro-3-trifluoromethoxybenzene; Benzene, 1-(bromomethyl)-2-fluoro-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-2-Fluoro-3-(Trifluoromethoxy)Benzene is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.