Description

2-Bromo-3-Carboxy-Alpha,Alpha,α-Trifluoroanisole is a high-value, multi-functional fluorinated aromatic building block. This compound is engineered to introduce both bromo and trifluoromethoxy substituents into complex molecular architectures, enabling precise structural modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique solubility, chemical resistance, and surface properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck) for further functionalization.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries in medicinal chemistry.

Basic Information

Product Name	2-Bromo-3-Carboxy-Alpha,Alpha,α-Trifluoroanisole
CAS No.	1159512-46-5
Molecular Formula	C9H4BrF3O3
Molecular Weight	288.03 g/mol
Synonyms	2-Bromo-3-(trifluoromethoxy)benzoic acid; 3-Bromo-2-(trifluoromethoxy)benzoic acid; 2-Bromo-alpha,alpha,α-trifluoro-3-methoxybenzoic acid; Benzoic acid, 2-bromo-3-(trifluoromethoxy)-; 2-Bromo-3-trifluoromethoxybenzoic acid; 1159512-46-5; 2-Bromo-3-carboxy-α,α,α-trifluoroanisole
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Carboxy-Alpha,Alpha,α-Trifluoroanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.