Description

Boc-Dl-(2-Bromophenyl)Glycine is a protected amino acid derivative featuring a brominated aromatic side chain. This compound is a crucial chiral building block and intermediate in modern organic synthesis, particularly valued for its role in constructing complex peptide mimetics and pharmaceutical scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and bioactive compounds. Its structural features make it indispensable for medicinal chemistry and advanced material science applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including protease inhibitors and receptor antagonists.
• Peptidomimetics Synthesis: Used to incorporate non-natural, bromine-functionalized phenylglycine residues into peptide chains to enhance stability, binding affinity, and metabolic resistance.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged molecules used in studying biological pathways and protein interactions.
• Organocatalyst & Ligand Preparation: Acts as a precursor for synthesizing novel chiral catalysts and ligands for asymmetric synthesis.
• Material Science Research: Employed in the development of specialized polymers and advanced organic materials with unique electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	Boc-Dl-(2-Bromophenyl)Glycine
CAS No.	1159503-14-6
Molecular Formula	C₁₃H₁₆BrNO₄
Molecular Weight	330.18 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-bromo-DL-phenylglycine; (RS)-2-[(tert-Butoxycarbonyl)amino]-2-(2-bromophenyl)acetic acid; Boc-2-Br-DL-Phg-OH; DL-2-Bromo-N-Boc-phenylglycine; tert-Butyl (2-bromophenyl)(carboxymethyl)carbamate; (2-Bromophenyl)((tert-butoxycarbonyl)amino)acetic acid; BOC-DL-2-BROMOPHENYLGLYCINE; N-Boc-2-bromo-DL-phenylglycine
EINECS	Contact for details

Quality Control

Our Boc-Dl-(2-Bromophenyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details (racemic mixture)
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.