Description

1-Pyrrolidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative featuring a pyrrolidine scaffold with a pendant aminomethyl group. This compound matters as a versatile and critical pharmaceutical intermediate and building block for medicinal chemistry research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening libraries and for constructing novel molecular scaffolds to explore structure-activity relationships (SAR).
• Peptidomimetics Synthesis: Serves as a proline analog or constrained amino acid surrogate in the design of peptide-like molecules with enhanced metabolic stability.
• Agrochemical Research: Employed as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Useful for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation & Linker Chemistry: The protected amine and ester functionalities allow for selective deprotection and conjugation in bioconjugation applications.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	1158758-67-8
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	tert-Butyl 3-(aminomethyl)-3-methylpyrrolidine-1-carboxylate; 3-(Aminomethyl)-3-methylpyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-(aminomethyl)-3-methylpyrrolidine; Boc-3-(aminomethyl)-3-methylpyrrolidine; 3-Methyl-3-(aminomethyl)pyrrolidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(aminomethyl)-3-methylpyrrolidine; (3-Methyl-3-pyrrolidinylmethyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 3-(Aminomethyl)-3-Methyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.