Description

3-[(2-Fluorophenyl)Methyl]Hexahydro-1H-Azepine is a fluorinated azepane derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific stereochemistry and fluorine substitution are critical for bioactivity. Pharmaceutical R&D teams and fine chemical manufacturers need it to create new therapeutic candidates, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Biology & Proteomics: Serves as a scaffold or linker in the design of molecular probes and enzyme inhibitors for target validation studies.
• Material Science: Potential precursor for specialty polymers and liquid crystals, leveraging the azepane ring structure.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel synthetic route exploration.

Basic Information

Product Name	3-[(2-Fluorophenyl)Methyl]Hexahydro-1H-Azepine
CAS No.	1158747-37-5
Molecular Formula	C13H18FN
Molecular Weight	207.29 g/mol
Synonyms	3-[(2-Fluorobenzyl)]Hexahydro-1H-Azepine; 1H-Azepine, Hexahydro-3-[(2-Fluorophenyl)Methyl]-; 3-(2-Fluorobenzyl)Hexahydroazepine; 3-(2-Fluorobenzyl)Azepane; N-(2-Fluorobenzyl)Azepane; Azepane, 3-[(2-Fluorophenyl)Methyl]-; 1158747-37-5; 3-(2-Fluorobenzyl)Perhydroazepine
EINECS	Contact for details

Quality Control

Our 3-[(2-Fluorophenyl)Methyl]Hexahydro-1H-Azepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring supply reliability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.