Description

6-(3-Diphenylphosphanylbiphenyl-2-Yloxy)-2,2-Dimethyl-4,4,8,8-Tetraphenyltetrahydro-[1,3]Dioxolo[4,5-E][1,3,2]Dioxaphosphepine is a sophisticated, sterically hindered phosphine ligand designed for advanced catalytic applications. Its unique structure provides exceptional electronic and steric tuning, making it a critical component for developing highly selective and active transition metal catalysts. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to optimize challenging cross-coupling and hydrogenation reactions.

Application

• Catalyst Ligand for Cross-Coupling Reactions: A key ligand in palladium-catalyzed Suzuki-Miyaura, Buchwald-Hartwig, and Negishi couplings for C-C and C-N bond formation in complex molecule synthesis.
• Asymmetric Synthesis: Employed in the development of chiral catalysts for enantioselective hydrogenation and other transformations to produce single-isomer pharmaceutical intermediates.
• Fine Chemical & Pharmaceutical Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules where high selectivity and yield are paramount.
• Polymerization Catalysis: Acts as a ligand in metal-catalyzed polymerization processes to control polymer microstructure and molecular weight.
• Material Science Research: Utilized in the development of novel organometallic complexes and catalysts for advanced material applications.
• Agrochemical Synthesis: Facilitates the production of advanced, high-performance agrochemicals through efficient catalytic steps.

Basic Information

Product Name	6-(3-Diphenylphosphanylbiphenyl-2-Yloxy)-2,2-Dimethyl-4,4,8,8-Tetraphenyltetrahydro-[1,3]Dioxolo[4,5-E][1,3,2]Dioxaphosphepine
CAS No.	1158430-46-6
Molecular Formula	C55H45O4P
Molecular Weight	824.91 g/mol
Synonyms	DTBPPHOS; 2,2-Dimethyl-4,4,8,8-tetraphenyl-6-[3-(diphenylphosphino)biphenyl-2-yloxy]-1,3,5,7,2λ⁵,4λ⁵,6λ⁵,8λ⁵-tetroxatetraphosphocine; 6-(3-Diphenylphosphanyl[1,1'-biphenyl]-2-yloxy)-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3,5,7,2λ⁵,4λ⁵,6λ⁵,8λ⁵-tetroxatetraphosphocine; Dt-Bu-Phos; DtBuPhos; DtBuPhos Ligand; Contact for details on additional trade names.
EINECS	Contact for details.

Quality Control

Our production of 6-(3-Diphenylphosphanylbiphenyl-2-Yloxy)-2,2-Dimethyl-4,4,8,8-Tetraphenyltetrahydro-[1,3]Dioxolo[4,5-E][1,3,2]Dioxaphosphepine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Elemental Analysis	Conforms to theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.