Description

1-(Methoxyacetyl)-1,4-Diazepane Hydrochloride is a high-purity chemical intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmacologically active molecules, particularly within the heterocyclic chemistry space. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring diazepane-based chemistry.

Basic Information

Product Name	1-(Methoxyacetyl)-1,4-Diazepane Hydrochloride
CAS No.	1158294-49-5
Molecular Formula	C9H17ClN2O2
Molecular Weight	220.70 g/mol
Synonyms	1-(Methoxyacetyl)-1,4-diazepane hydrochloride; 1,4-Diazepane, 1-(methoxyacetyl)-, hydrochloride; 1-(Methoxyacetyl)homopiperazine hydrochloride; Homopiperazine, 1-(methoxyacetyl)-, hydrochloride; N-(Methoxyacetyl)homopiperazine hydrochloride; 1,4-Diazepan-1-yl 2-methoxy-2-oxoethan-1-ium chloride
EINECS	Contact for details

Quality Control

Our 1-(Methoxyacetyl)-1,4-Diazepane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.