Description

2-(2,4-Difluorophenyl)Cyclopropanecarboxylic Acid CAS NO 1157642-22-2 is a high-value, multi-functional organic building block featuring a cyclopropane ring and a difluorinated aromatic system. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable metabolic stability and bioactivity. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluorophenyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where the cyclopropane unit can influence material rigidity and thermal properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	2-(2,4-Difluorophenyl)Cyclopropanecarboxylic Acid
CAS No.	1157642-22-2
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	2-(2,4-Difluorophenyl)cyclopropanecarboxylic acid; 2-(2,4-Difluorophenyl)cyclopropane-1-carboxylic acid; 1-Cyclopropanecarboxylic acid, 2-(2,4-difluorophenyl)-; 1157642-22-2; 2,4-Difluorophenylcyclopropanecarboxylic Acid; (2,4-Difluorophenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(2,4-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade materials for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.