Description

2-(3-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile is a specialized nitrile-containing piperidine derivative, serving as a crucial advanced pharmaceutical intermediate. Its molecular structure, featuring both a hydroxymethyl and a benzonitrile moiety, makes it a versatile building block for constructing complex bioactive molecules. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Chemical Research & Development: Serves as a versatile precursor for medicinal chemistry and process chemistry, enabling the exploration of new chemical entities.
• Ligand and Catalyst Development: The nitrile and hydroxymethyl functional groups make it a candidate for developing chiral ligands or organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(3-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile
CAS No.	1156672-42-2
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	1-[(2-Cyanophenyl)methyl]-3-piperidinemethanol; 3-(Hydroxymethyl)-1-[(2-cyanophenyl)methyl]piperidine; 2-[(3-Hydroxymethylpiperidin-1-yl)methyl]benzonitrile; 1-(2-Cyanobenzyl)-3-piperidinemethanol; 2-((3-(Hydroxymethyl)piperidin-1-yl)methyl)benzonitrile; Benzonitrile, 2-[(3-(hydroxymethyl)-1-piperidinyl)methyl]-
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxymethyl-Piperidin-1-Ylmethyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current Good Manufacturing Practice (cGMP) principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.