Description

(R)-(+)-[(R)-2-Dicyclohexylphosphinoferrocenyl](N,n-Dimethylamino)(2-Dicyclohexylphosphinophenyl)Methane, Min. 97% is a highly specialized, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. This compound matters because it provides exceptional enantioselectivity and activity in critical transition-metal-catalyzed reactions, enabling the synthesis of complex chiral molecules with high purity. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for developing new active ingredients and advanced materials.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral pharmaceutical intermediates.
• Asymmetric C-C Bond Formation: Catalyzes key cross-coupling and addition reactions, such as Suzuki-Miyaura and Heck reactions, with high stereocontrol.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and scalable production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and oncology.
• Agrochemical Research: Used in the development of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Fine Chemical and Fragrance Manufacturing: Facilitates the synthesis of enantiomerically pure flavors, fragrances, and advanced organic materials.
• Academic and Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research.

Basic Information

Item	Details
Product Name	(R)-(+)-[(R)-2-Dicyclohexylphosphinoferrocenyl](N,n-Dimethylamino)(2-Dicyclohexylphosphinophenyl)Methane, Min. 97%
CAS No.	1156547-61-3
Molecular Formula	C43H57FeNP2
Molecular Weight	705.71 g/mol
Synonyms	(R)-JOSIPHOS SL-J009-1; (R)-(+)-1-[(S)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine (common mis-assignment check); Josiphos-type ligand; Chiral ferrocenyl diphosphine; (R)-[(R)-2-(Dicyclohexylphosphino)ferrocenyl](N,N-dimethylamino)(2-dicyclohexylphosphinophenyl)methane; SL-J009-1; Asymmetric hydrogenation ligand; Ferrocene-based phosphine ligand.
EINECS	Contact for details

Quality Control

Every batch of our (R)-(+)-[(R)-2-Dicyclohexylphosphinoferrocenyl](N,n-Dimethylamino)(2-Dicyclohexylphosphinophenyl)Methane is produced and tested under strict quality management systems. We guarantee a minimum purity of 97%, with rigorous analytical controls including HPLC, NMR (¹H and ³¹P), and chiral analysis to ensure identity, potency, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0%
³¹P NMR	Conforms to reference
Loss on Drying	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.