Description

[2-(2,2,2-Trifluoroethoxy)Cyclohexyl]Methanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a cyclohexyl backbone with a trifluoroethoxy substituent, offering a distinct electronic and steric profile for modulating the properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with tailored surface properties and chemical resistance.
• Chemical Biology Probe: Useful for incorporating a fluorinated, amine-reactive handle into biomolecules for study via techniques like 19F NMR.

Basic Information

Product Name	[2-(2,2,2-Trifluoroethoxy)Cyclohexyl]Methanamine
CAS No.	1155125-61-3
Molecular Formula	C9H16F3NO
Molecular Weight	211.22 g/mol
Synonyms	1-[(2,2,2-Trifluoroethoxy)cyclohexyl]methanamine; (2-(2,2,2-Trifluoroethoxy)cyclohexyl)methanamine; 2-(2,2,2-Trifluoroethoxy)cyclohexanemethanamine; Cyclohexanemethanamine, 2-(2,2,2-trifluoroethoxy)-; 1-(2,2,2-Trifluoroethoxycyclohexyl)methylamine; 2-(Trifluoroethoxy)cyclohexylmethylamine; 2-(2,2,2-Trifluoroethoxy)-1-cyclohexylmethanamine
EINECS	Contact for details

Quality Control

Our [2-(2,2,2-Trifluoroethoxy)Cyclohexyl]Methanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.